What Is Pregabalin (Lyrica)?
Pregabalin, sold under the brand name Lyrica, is an anticonvulsant and analgesic medication primarily used to treat neuropathic pain, fibromyalgia, and generalised anxiety disorder (GAD). It is classified as a Schedule 3 controlled substance in the UK. Buy Pregabalin (Lyrica) 300mg from QuickMedzUK — discreet, fast UK delivery.
What Is Pregabalin Used For?
- Neuropathic pain — diabetic neuropathy, post-herpetic neuralgia (shingles pain), spinal cord injury pain
- Fibromyalgia — widespread musculoskeletal pain
- Generalised Anxiety Disorder (GAD)
- Partial-onset seizures — used as add-on therapy in epilepsy
Pregabalin Dosage
For neuropathic pain: start at 75mg twice daily, increasing to 150mg twice daily after one week. Maximum dose is 600mg/day.
For generalised anxiety: 150–600mg/day in 2–3 divided doses.
Dose adjustments are required for patients with kidney impairment. Pregabalin should always be tapered off slowly to avoid withdrawal symptoms.
Pregabalin vs Gabapentin
Pregabalin and gabapentin work by the same mechanism (blocking voltage-gated calcium channels), but pregabalin has higher bioavailability (90% vs 33–60% for gabapentin), more predictable pharmacokinetics, and a more consistent dose-response. Pregabalin is generally considered the more potent and reliable choice for neuropathic pain.
Side Effects of Pregabalin
Very common (affecting more than 1 in 10 people): dizziness, drowsiness, weight gain, peripheral oedema (swelling of hands and feet). The sedating effects are amplified significantly by opioids — this combination has been associated with fatal respiratory depression. Never combine pregabalin with opioids without medical supervision.
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Disclaimer: Pregabalin is a Schedule 3 controlled drug in the UK. It must be prescribed by a licensed practitioner.